Posts

The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets

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New datascope available in R2: open online Genomics Analysis and Visualization Platform ( https://r2.amc.nl ). "The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets" by Jaco Knol et. al under the guidance of Connie Jimenez published in Cancer Cell. "Most cancer proteomics studies to date have focused on a single cancer type. We report The Pan-Cancer Proteome Atlas (TPCPA) based on data-independent acquisition mass spectrometry, to better understand cancer biology and identify therapeutic targets and biomarkers. TPCPA includes 9,670 proteins derived from 999 primary tumors representing 22 cancer types. All TPCPA data can be queried in a dedicated web resource." The datascope can be acccessed here http://r2platform.com/TPCPA dataviz, proteomics, datascience, cancer

Unlock the Power of Biomedical Data with the R2 Platform

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In today's rapidly evolving landscape of biomedical research, access to high-quality, well-curated data is paramount. Researchers and clinicians alike are constantly seeking efficient ways to explore, analyze, and ultimately translate complex biological information into tangible advancements in patient care. Enter the R2 Platform ( r2.amc.nl ) – your gateway to a wealth of expertly managed biomedical data. Developed and maintained by Amsterdam UMC, the R2 platform stands as a robust and user-friendly resource designed to empower your research endeavors. Whether you're a seasoned bioinformatician, a dedicated clinician, or a curious researcher venturing into the world of biomedical data, R2 offers a comprehensive suite of tools and datasets to fuel your discoveries. What makes the R2 Platform stand out? Curated and Integrated Datasets: Tired of sifting through disparate data sources? R2 brings together a diverse collection of meticulously curated and integrated datasets, spann...

Unleash the power of genomics without writing a single line of code

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 ðŸ§¬ Unleash the power of genomics without writing a single line of code! The R2 platform ( https://r2.amc.nl ) puts advanced genomics data analysis in YOUR hands - even if you don't have bioinformatics expertise. Imagine exploring differential expression analyses, performing survival analyses with optimal cutoffs, and creating gene set signatures - all through an intuitive, visual interface designed for biomedical researchers. From single-cell RNA-seq exploration to multi-omics integration, our platform has helped researchers publish in journals like Nature and Cell, with over 2,900 citations in PubMed! ➡️ Visit https://r2.amc.nl today and join thousands of scientists making genomics discoveries without coding barriers. Your next breakthrough is just a click away. #GenomicResearch #NoCode #DataScience #Bioinformatics #MedicalResearch #R2Platform

Podcast on the R2 genomics analysis and visualization platform

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Don't feel like reading about the R2 open online data science platform for biomedical researchers? Then simply listen to a podcast on the subject here:  PodCast on R2 In 15 minutes you will get a grasp on the conscept behind te platform.

Create a visual Fisher's Exact plot in a few simple clicks in the R2 Genomics Analysis & Visualization platform

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Create a visual Fisher's Exact plot in a few simple clicks in the R2 Genomics Analysis & Visualization platform ( https://r2.amc.nl ). Just see the whole process in action in the illustration below. The Fisher's Exact test is often used to demonstrate whether the proportions of 2 different categorical variables are equal to the expectation. A significant p-value then informs you that this is unlikely (when used as a 2-sided test). Within R2, we add a visual element to such a test, where you can see the different groups in the contingency table as separate dots. These dots, are linked to actual samples in the data set, and can thus also be decorated using their meta data (color by a grouping variable), or even by the expression of any gene. As such you can add another layer in your interpretation. Just have a look at the animation above on how you can easily use this powerful option within the R2platform. The R2 open access online data science platform, designed for biomedic...

Create a stacked bar plot in a few simple clicks in the R2

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Create a stacked bar plot in a few simple clicks in the R2 Genomics Analysis & Visualization platform (https://r2.amc.nl). Just see the whole process in action in the illustration below. The R2 open access online data science platform, designed for biomedical researchers, has more than 2,600 public resources (totalling >4,000,000 samples combined) available for instant analysis. Academic usage of R2 is free, so direct your browser to https://r2.amc.nl and start exploring TCGA, DepMap, GTeX or one of the other 2,600 resources.

Explore data-driven embeddings, such as UMAP, tSNE etc on more than 2500 public resources in the 'sample maps' tool of the R2 platform

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Explore data-driven embeddings, such as UMAP, tSNE etc on more than 2500 public resources in the 'sample maps' tool of the R2 platform. This is just one of the many avenues R2 has to offer for scientists who are not experts in bioinformatics or coding. R2: open online data science platform for biomedical researchers ( https://r2.amc.nl )